Thursday, July 17, 2014
Quick DNA Tests Crack Medical Mysteries Otherwise Missed__Faten
Summary:
According to
the article “Quick DNA Crack Medical Mysteries Otherwise Missed” that had written
by RICHARD HARRIS mentioned the researchers found a new technique
way to diagnose infectious diseases. Instead of guessing or assumption what
patient could have and making different kind of tests by taking a sample of
infected person’s blood and search through the DNA in it, by looking for
sequences that match with virus, bacterium, a fungue or parasite.
Regarding to the article the
first result for this technique which called Next Generation Sequencing is
reported by scientists who are from the University of San Francisco. This
technique was tested on a patient called Andrea Struve, a 21-year-old
who returned from Australia with nasty set symptoms by Dr. Charles Chiu, who is
running the study, and his colleagues. They made the experiment by extracting DNA
from Struve’s blood and run it through superfast sequencing machine then
compared the DNA they found with a huge library of all kind of DNA sequences of
infectious agents. They found that she infected with virus related to chicken
box-
one that
normally causes a roseola rash in young children. When Struve went to
the doctor, Her doctor made a bunch of guesses about the infectious cause, but
all the tests came back negative.
Moreover, Dr. Chiu study involved
a medical mystery about 14 years old boy in Wisconsin with brain inflammation,
so Dr. Chiu got the sample in few days and with 48 hours he was able to run the
assay and detect the organism which is a bacterium called Leptospira and which
is common in the tropics that cause the infection. Dr. Chiu and his colleague think
the boy picked the microbe while he taking a swim during a family vacation in Puerto
Rico. The boy recovered after intensive Penicillin treatment.
This technique has been tested in
more than 30 cases so far by Dr. Chiu. He and his colleague have been able to
identify an infectious culprit about 25 percent of the time. Some of the
remaining cases turned out not to be infections at all. This technique is still
experimental and it is done at university and cost about 1,000$ in labor and
material without including the expensive machinery. Dr. Chiu hopes in time it will become the
go-to analysis when traditional blood tests don't provide the answer.
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